Structure of the Specific Oligosaccharides from the Glycopeptidolipid Antigens of Serovars in the Mycobacterium auium-Mycobacterium
نویسنده
چکیده
The specific oligosaccharide units of the C-mycosidic glycopeptidolipid antigens from serovarieties in the Mycobacterium avium-Mycobacterium intracellulare-Mycobacterium scrofulaceum complex were liberated as oligosaccharide alditols by treatment of the glycopeptidolipids with alkaline borohydride. The complete structures of the oligosaccharide alditols have been derived from their ‘H-NMR spectra or those of their permethylated (or pertrideuteriomethylated) derivatives, the mass spectra of the methylated derivatives, and from methylation fragmentation analysis. Periodate oxidation was also used to confirm the position of the link between the ultimate and penultimate sugars. The following structures are proposed (with some extrapolation of enantiomeric configurations where evidence for assignment is not yet complete) for the oligosaccharide alditols:
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